Human Apo B-48 ELISA「シバヤギ」 (AKHB48) ／ Human Apo B-48 ELISA KIT
Original reports
# Improvement of pulse wave velocity and metabolic cardiovascular risk parameters through egg protein hydrolysate intake: A randomized trial in overweight or obese subjects with impaired glucose tolerance or type 2 diabetes
Jogchum Plat, Nadine Severins, Ronald P. Mensink
Journal of Functional Foods, Vol.52, January 2019, Pages 418-423
# Characterizing familial chylomicronemia syndrome: Baseline data of the APPROACH study.
Blom DJ, O’Dea L, Digenio A, Alexander VJ, Karwatowska-Prokopczuk E, Williams KR, Hemphill L, Muniz-Grijalvo O, Santos RD, Baum S, Witztum JL.
J Clin Lipidol. 2018 Sep – Oct;12(5):1234-1243.e5.
# Plasma PCSK9 correlates with apoB-48-containing triglyceride-rich lipoprotein production in men with insulin resistance.
Drouin-Chartier JP, Tremblay AJ, Hogue JC, Lemelin V, Lamarche B, Couture P.
J Lipid Res. 2018 Aug;59(8):1501-1509.
# Differential associations between plasma concentrations of insulin and glucose and intestinal expression of key genes involved in chylomicron metabolism.
Drouin-Chartier JP, Tremblay AJ, Lemelin V, Lamarche B, Couture P.
Am J Physiol Gastrointest Liver Physiol. 2018 Aug 1;315(2):G177-G184.
# Theobromine Does Not Affect Fasting and Postprandial HDL Cholesterol Efflux Capacity, While It Decreases Fasting miR-92a Levels in Humans.
Talbot CPJ, Mensink RP, Smolders L, Bakeroot V, Plat J.
Mol Nutr Food Res. 2018 Jul;62(13):e1800027.
# Effects of acute exercise on monocyte subpopulations in metabolic syndrome patients.
Wonner R, Wallner S, Orso E, Schmitz G
Cytometry B Clin Cytom. 2018 Jul;94(4):596-605.
# A pre-meal of whey proteins induces differential effects on glucose and lipid metabolism in subjects with the metabolic syndrome: a randomised cross-over trial.
Bjornshave A, Holst JJ, Hermansen K.
Eur J Nutr. 2018 Apr 6.
# Effects of a diet rich in arabinoxylan and resistant starch compared with a diet rich in refined carbohydrates on postprandial metabolism and features of the metabolic syndrome.
Schioldan AG, Gregersen S, Hald S, Bjornshave A, Bohl M, Hartmann B, Holst JJ, Stodkilde-Jorgensen H, Hermansen K.
Eur J Nutr. 2018 Mar;57(2):795-807.
# Evidence for increased chylomicron remnants in rheumatoid arthritis.
Burggraaf B, van Breukelen-van der Stoep DF, van Zeben J, van der Meulen N, van de Geijn GM, Liem A, Valdivielso P, Rioja Villodres J, Ramirez-Bollero J, van der Zwan E, Castro Cabezas M.
Eur J Clin Invest. 2018 Feb;48(2).
# Pre-Meal Effect of Whey Proteins on Metabolic Parameters in Subjects with and without Type 2 Diabetes: A Randomized, Crossover Trial.
Bjornshave A, Holst JJ, Hermansen.
Nutrients. 2018 Jan 25;10(2). pii: E122.
# Postprandial VLDL-TG metabolism in type 2 diabetes.
Søndergaard E, Johansen RF, Jensen MD, Nielsen S
Metabolism. 2017 Oct;75:25-35.
# Differential impact of the cheese matrix on the postprandial lipid response: a randomized, crossover, controlled trial.
Drouin-Chartier JP, Tremblay AJ, Maltais-Giguère J, Charest A, Guinot L, Rioux LE, Labrie S, Britten M, Lamarche B, Turgeon SL, Couture P.
Am J Clin Nutr. 2017 Oct 4.
# Infant milk fat droplet size and coating affect postprandial responses in healthy adult men: a proof-of-concept study.
Baumgartner S, van de Heijning BJM, Acton D, Mensink RP.
Eur J Clin Nutr. 2017 Sep;71(9):1108-1113.
# The elevation of plasma concentrations of apoB-48-containing lipoproteins in familial hypercholesterolemia is independent of PCSK9 levels.
Drouin-Chartier JP, Hogue JC, Tremblay AJ, Bergeron J, Lamarche B, Couture P.
Lipids Health Dis. 2017 Jun 15;16(1):119.
# An acute intake of theobromine does not change postprandial lipid metabolism, whereas a high-fat meal lowers chylomicron particle number
Lotte Smolders, Ronald P. Mensink, Jogchum Plat
Nutrition Research, Vol.40, Apr 2017, Pages 85-94
# C-reactive protein levels are inversely correlated with the apolipoprotein B-48-containing triglyceride-rich lipoprotein production rate in insulin resistant men.
Drouin-Chartier JP, Tremblay AJ, Hogue JC, Leclerc M, Labonté MÈ, Marin J, Lamarche B, Couture P.
Metabolism. 2017 Mar;68:163-172.
# Dietary fat and physiological determinants of plasma chylomicron remnant homoeostasis in normolipidaemic subjects: insight into atherogenic risk.
Irawati D, Mamo JC, Slivkoff-Clark KM, Soares MJ, James AP.
Br J Nutr. 2017 Feb;117(3):403-412.
# Effects of a diet rich in arabinoxylan and resistant starch compared with a diet rich in refined carbohydrates on postprandial metabolism and features of the metabolic syndrome.
Schioldan AG, Gregersen S, Hald S, Bjørnshave A, Bohl M, Hartmann B, Holst JJ, Stødkilde-Jørgensen H, Hermansen K.
Eur J Nutr. 2017 Jan 9.
# The Effects of a Hypocaloric Diet on Diet-Induced Thermogenesis and Blood Hormone Response in Healthy Male Adults: A Pilot Study.
Ishii S, Osaki N, Shimotoyodome A.
J Nutr Sci Vitaminol (Tokyo). 2016;62(1):40-6.
# Effects of a Plant Sterol or Stanol Enriched Mixed Meal on Postprandial Lipid Metabolism in Healthy Subjects.
Baumgartner S, Mensink RP, Plat J
PLoS One. 2016 Sep 9;11(9):e0160396.
# Plasma triglyceride and high density lipoprotein cholesterol are poor surrogate markers of pro-atherogenic chylomicron remnant homeostasis in subjects with the metabolic syndrome.
Irawati D, Mamo JC, Dhaliwal SS, Soares MJ, Slivkoff-Clark KM, James AP.
Lipids Health Dis. 2016 Sep 29;15(1):169.
# Adiposity in Children and CVD Risk: ApoB48 Has a Stronger Association With Central Fat Than Classic Lipid Markers.
Wilke MS, Maximova K, Henderson M, Levy E, Paradis G, O’Loughlin J, Tremblay A, Proctor SD
J Clin Endocrinol Metab. 2016 Jul;101(7):2915-22.
# Effects of angiopoietin-like protein 3 deficiency on postprandial lipid and lipoprotein metabolism.
Minicocci I, Tikka A, Poggiogalle E, Metso J, Montali A, Ceci F, Labbadia G, Fontana M, Di Costanzo A, Maranghi M,
Rosano A, Ehnholm C, Donini LM, Jauhiainen M, Arca M.
J Lipid Res. 2016 Jun;57(6):1097-107.
# Increased postprandial apolipoprotein B-48 level after a test meal in diabetic patients: A multicenter, cross-sectional study.
Park CY, Park JY, Choi J, Kim DJ, Park KS, Yoon KH, Lee MK, Park SW
Metabolism. 2016 Jun;65(6):843-51.
# Effects of acute exercise on monocyte subpopulations in metabolic syndrome patients.
Wonner R, Wallner S, Orsó E, Schmitz G
Cytometry B Clin Cytom. 2016 Jun 10.
# Effects of roux-en-Y gastric bypass surgery on postprandial fructose metabolism.
Surowska A, De Giorgi S, Theytaz F, Campos V, Hodson L, Stefanoni N, Rey V, Schneiter P, Laville M, Giusti V, Gabert L, Tappy L.
Obesity (Silver Spring). 2016 Mar;24(3):589-96.
# Minor Contribution of Endogenous GLP-1 and GLP-2 to Postprandial Lipemia in Obese Men
Niina Matikainen, Elias Björnson, Sanni Söderlund, Christofer Borén, Björn Eliasson, Kirsi H. Pietiläinen, Leonie H. Bogl, Antti Hakkarainen, Nina Lundbom, Angela Rivellese, Gabriele Riccardi, Jean-Pierre Després, Natalie Alméras, Jens Juul Holst, Carolyn F. Deacon, Jan Borén, and Marja-Riitta Taskinen
PLoS One. 2016; 11(1): e0145890.
# Distinct Metabolism of Apolipoproteins (a) and B-100 within Plasma Lipoprotein(a)
Margaret R. Diffenderfer, Stefania Lamon-Fava, Santica M. Marcovina, P. Hugh R. Barrett, Julian Lel, Gregory G. Dolnikowski, Lars Berglund, Ernst J. Schaefer
Metabolism, Volume 65, Issue 4, Apr. 2016, Pages 381–390
# The effect of glucose when added to a fat load on the response of glucagon-like peptide-1 (GLP-1) and apolipoprotein B-48 in the postprandial phase.
Zemánková K, Mrázková J, Piťha J, Kovář J.
Physiol Res. 2015;64 Suppl 3:S363-9.
# Lipoprotein Metabolism in APOB L343V Familial Hypobetalipoproteinemia
Amanda J. Hooper, Liesl Heeks, Ken Robertson, Danie Champain, Jianmin Hua, Swithin Song, Klaus G. Parhofer, P. Hugh R. Barrett, Frank M. van Bockxmeer, and John R. Burnett
J Clin Endocrinol Metab. 2015 Nov;100(11):E1484-90
# In Vivo Evidence for Chylomicrons as Mediators of Postprandial Inflammation
de Vries MA, Klop B, Alipour A, van de Geijn GM, Prinzen L, Liem AH, Valdivielso P, Rioja Villodres J, Ramírez-Bollero J, Castro Cabezas M
Atherosclerosis. 2015 Oct 23;243(2):540-545.
# Hypertriglyceridemic subjects exhibit an accumulation of small dense chylomicron particles in the fasting state
Deasy Irawati, John C.L. Mamo, Mario J. Soares, Karin M. Slivkoff-Clark, Anthony P. James
Atherosclerosis, Volume 243, Issue 1, November 2015, Pages 236–241
# The expression of genes involved in jejunal lipogenesis and lipoprotein synthesis is altered in morbidly obese subjects with insulin resistance
Carolina Gutierrez-Repiso, Francisca Rodriguez-Pacheco, Juan Garcia-Arnes, Sergio Valdes, Montserrat Gonzalo, Federico Soriguer, Francisco J Moreno-Ruiz, Alberto Rodriguez-Cañete, Jose L Gallego-Perales, Guillermo Alcain-Martinez, Luis Vazquez-Pedreño, Soledad Lopez-Enriquez, Sara Garcia-Serrano, Lourdes Garrido-Sanchez and Eduardo Garcia-Fuentes
Laboratory Investigation , (14 September 2015) | doi:10.1038/labinvest.2015.115
# Ext1 heterozygosity causes a modest effect on postprandial lipid clearance in humans.
Mooij HL, Bernelot Moens SJ, Gordts PL, Stanford KI, Foley EM, van den Boogert MA, Witjes JJ, Hassing HC, Tanck MW, van de Sande MA, Levels JH5, Kastelein JJ, Stroes ES, Dallinga-Thie GM, Esko JD, Nieuwdorp M.
J Lipid Res. Vol.56(3), p665-73, Mar 2015.
# Dairy proteins, dairy lipids, and postprandial lipemia in persons with abdominal obesity (DairyHealth): a 12-wk, randomized, parallel-controlled, double-blinded, diet intervention study.
Bohl M, Bjørnshave A, Rasmussen KV, Schioldan AG, Amer B, Larsen MK, Dalsgaard TK1, Holst JJ, Herrmann A, O’Neill S, O’Driscoll L, Afman L, Jensen E, Christensen MM, Gregersen S, Hermansen K.
Am J Clin Nutr. Vol.101(4), p870-8, Jan 2015.
# The effect of a low fructose and low glycemic index/load (FRAGILE) dietary intervention on indices of liver function, cardiometabolic risk factors, and body composition in children and adolescents with nonalcoholic fatty liver disease (NAFLD)
D.R. Mager, I.R. Iniguez, S. Gilmour, J. Yap.
JPEN J Parenter Enteral Nutr, Vol.39(1), p73-84, Jan 2015.
# Genetic Variation in Heparan Sulfate Proteoglycans Modestly Affect Postprandial Lipid Clearance in Humans
Hans L. Mooij, Sophie J. Bernelot Moens, Philip L.S.M. Gordts, Kristin I. Stanford, Erin M. Foley, Marjolein A. W. van den Boogert, Julia J. Witjes, H. Carlijne Hassing, Michael W. Tanck, Michiel A. J. van de Sande, J. Han Levels, John J. P. Kastelein, Erik S. G. Stroes, Geesje M. Dallinga-Thie, Jeff D. Esko and Max Nieuwdorp
The Journal of Lipid Research, jlr.M053504. 2015.
# An interesterified palm olein test meal decreases early-phase postprandial lipemia compared to palm olein: a randomized controlled trial
Wendy L. Hall, Marcela Fiuza Brito, Junlan Huang, Lucy V. Wood, Androulla Filippou, Thomas A. B. Sanders, Sarah E. E. Berry
Lipids, Vol.49(9), p895-904. Sep 2014.
# Effects of sitagliptin therapy on markers of low-grade inflammation and cell adhesion molecules in patients with type 2 diabetes
Andre J. Tremblay, Benoit Lamarche, Carolyn F. Deacon, S. John Weisnagel, Patrick Couture
Metabolism, Vol.63(9), p1141-1148, Sep 2014.
# Test meals rich in marine long-chain n-3 polyunsaturated fatty acids increase postprandial chylomicron response
E. Griffo, L. Di Marino, L. Patti, L. Bozzetto, G. Annuzzi, P. Cipriano, A. Mangione, G. Della Pepa, S. Cocozza, G. Riccardi, A.A. Rivellese
Nut Res, Vol.34(8), p661-666, Aug 2014.
# Sitagliptin, a DPP-4 Inhibitor, acutely inhibits intestinal lipoprotein particle secretion in healthy humans
Xiao C., Dash S., Morgantini C., PattersonBW. and Lewis GF.
Diabetes, Vol. 63(7), p2394-2401, Jul 2014.
# Favorable effects of ezetimibe alone or in association with simvastatin on the removal from plasma of chylomicrons in coronary heart disease subjects
Mangili OC, Moron Gagliardi AC, Mangili LC, Mesquita CH, Machado Cesar LA, Tanaka A, Schaefer EJ, Maranhao RC, Santos RD.
Atherosclerosis, Vol.233(1), p319-325, Mar 2014.
# Diets naturally rich in polyphenols improve fasting and postprandial dyslipidemia and reduce oxidative stress: a randomized controlled trial.
Annuzzi G1, Bozzetto L, Costabile G, Giacco R, Mangione A, Anniballi G, Vitale M, Vetrani C, Cipriano P, Della Corte G, Pasanisi F, Riccardi G, Rivellese AA.
Am J Clin Nutr. Vol.99(3), p463-471, Mar 2014.
# Dietary medium-chain triglyceride supplementation has no effect on apolipoprotein B-48 and apolipoprotein B-100 kinetics in insulin-resistant men.
Tremblay AJ1, Lamarche B, Labonte ME, Lepine MC, Lemelin V, Couture P.
Am J Clin Nutr. Vol.99(1), p54-61, Jan 2014.
# Key intestinal genes involved in lipoprotein metabolism are downregulated in dyslipidemic men with insulin-resistance
P. Couture, A.J. Tremblay, I. Kelly, V. Lemelin, A. Droit and B. Lamarche.
J Lipid Res, Vol.55(1), p128-137, Jan 2014.
# Patients with type 1 diabetes show signs of vascular dysfunction in response to multiple high-fat meals
Lassenius MI, Makinen VP, Fogarty CL, Peraneva L, Jauhiainen M, Pussinen PJ, Taskinen MR, Kirveskari J, Vaarala O, Nieminen JK, Horkko S, Kangas AJ, Soininen P, Ala-Korpela M, Gordin D, Ahola AJ, Forsblom C, Groop PH, Lehto M.
Nut Metab, 11:28, Jun 2014.
# Phosphorus supplement alters postprandial lipemia of healthy male subjects: a pilot cross-over trial
Jana Hazim, Sani Hlais, Hala Ghattas, Dareen Shatila, Maya Bassil and Omar Obeid
Lipids Health Dis, 13:109, Jul 2014.
# Long-term effects of Roux-en-Y gastric bypass on postprandial plasma lipid and bile acids kinetics in female non diabetic subjects: A cross-sectional pilot study
Sara De Giorgia, Vanessa Camposa, Leonie Eglia, Ulrike Toepelb, Guillaume Carrela, Bertrand Cariouc, Dominique Rainteaud, Philippe Schneitera, Luc Tappya, Vittorio Giustie
Clin Nutr, Sep 2014.
# Metabolic fate of fructose ingested with and without glucose in a mixed meal
Fanny Theytaz, Sara de Giorgi, Leanne Hodson, Nathalie Stefanoni, Valentine Rey,Philippe Schneiter, Vittorio Giusti and Luc Tappy
Nutrients, Vol.6(7), p2632-2649, Jul 2014
# Factors associated with postprandial lipemia and apolipoprotein A-V levels in individuals with familial combined hyperlipidemia
Almeda-Valdes P, Cuevas-Ramos D, Mehta R, Munoz-Hernandez L, Cruz-Bautista I, Perez-Mendez O, Teresa Tusie-Luna MT, Gomez-Perez FJ, Pajukanta P, Matikainen N, Taskinen MR and Aguilar-Salinas CA.
BMC Endocrine Disorders, 14:90, Nov 2014.
# Lactobacillus gasseri SBT2055 reduces postprandial and fasting serum non-esterified fatty acid levels in Japanese hypertriacylglycerolemic subjects
Ogawa A., Kadooka Y., Kato K., Shirouchi B. and Sato M.
Lipids Health Dis, Vol.13(36), Feb 2014.
# Diacylglycerol acyltransferase 1 inhibition with AZD7687 alters lipid handling and hormone secretion in the gut with intolerable side effects: a randomized clinical trial
H. Denison, C. Nilsson, L. Lofgren, A. Himmelmann, G. Martensson, M. Knutsson, A. AL-Shurbaji, H. Tornqvist, J.W. Eriksson
Diabetes, Obesity and Metabolism, Vol.16(4), p334-343, Apr 2014.
# Genetic Variation in SULF2 Is Associated with Postprandial Clearance of Triglyceride-Rich Remnant Particles and Triglyceride Levels in Healthy Subjects
N. Matikainen, M.A. Burza, S. Romeo, A. Hakkarainen, M. Adiels, L. Folkersen, P. Eriksson, N. Lundbom, E. Ehrenborg, M. Orho-Melander, M.-R Taskinen, J. Boren
PLOS ONE, Vol.8(11), e79473, Nov 2013.
van Meijl LE, Mensink RP.
Br J Nutr, Vol.110(3), p413-419, Aug 2013.
# Postprandial human triglyceride-rich lipoproteins increase chemoattractant protein secretion in human macrophages
M. Napolitano, K. M. Botham, E. Bravo
Cytokine, Vol.63(1), p18-26, Jul 2013.
# Pro-atherogenic lipid changes and decreased hepatic LDL receptor expression by tocilizumab in rheumatoid arthritis
Aart C. Stranga, Radjesh J. Bisoendial, Ruud S. Kootte, Dominik M. Schulte, Geesje M. Dallinga-Thie, Johannes H.M. Levels, Marc Kok, Koen Vos, Sander W. Tas, Uwe J.F. Tietge, Nike Müller, Matthias Laudes, Danielle M. Gerlag, Erik S.G. Stroes, Paul P. Tak
Atherosclerosis, Vol.229(1), p174–181, Jul 2013.
# A Meal High in Saturated Fat Evokes Postprandial Dyslipemia, Hyperinsulinemia, and Altered Lipoprotein Expression in Obese Children With and Without Nonalcoholic Fatty Liver Disease
Mager DR., Mazurak V., Rodriguez-Dimitrescu C., Vine D., Jetha M., Ball G., Yap Y.
JPEN J Parenter Enteral Nutr, Vol.37(4), p517-528, Jul 2013.
# Exercise prevents fructose-induced hypertriglyceridemia in healthy young subjects.
Egli L., Lecoultre V., Theytaz F., Campos V., Hodson L., Schneiter P., Mittendorfer B., Patterson BW., Fielding BA., Gerber PA., Giusti V., Berneis K., Tappy L.
Diabetes, Vol.62(7), p2259-2265, Jul 2013.
# Short-term, high-fat diet increases the expression of key intestinal genes involved in lipoprotein metabolism in healthy men
A.J. Tremblay, B. Lamarche, V. Guay, A. Charest, V. Lemelin, and P. Couture.
Am J Clin Nutr, Vol.98(1), p32-41, Jul 2013.
# Effect of combination therapy with fenofibrate and simvastatin on postprandial lipemia in the ACCORD lipid trial.
Reyes-Soffer G, Ngai CI, Lovato L, Karmally W, Ramakrishnan R, Holleran S, Ginsberg HN.
Diabetes Care. 2013 Feb;36(2):422-8. doi: 10.2337/dc11-2556. Epub 2012 Oct 1.
# Selective cannabinoid-1 receptor blockade benefits fatty acid and triglyceride metabolism significantly in weight-stable nonhuman primates
V. Vaidyanathan, R.A. Bastarrachea, P.B. Higgins, V.S. Voruganti, S. Kamath, N.V. DiPatrizio, D. Piomelli, A.G. Comuzzie, E.J. Parks
American Journal of Physiology – Endocrinology and Metabolism, Vol.303(5), p624-634, Sep 2012.
# Fasting apolipoprotein B48 is associated with asymptomatic peripheral arterial disease in type 2 diabetic subjects: A case-control study
Lapice E, Cipriano P, Patti L, Romano G, Vaccaro O, Rivellese A A.
Atherosclerosis, Vol.223(2), p504-506, Aug 2012.
# Rapid alternative absorption of dietary long-chain fatty acids with upregulation of intestinal glycosylated CD36 in liver cirrhosis
Yamamoto Y, Hiasa Y, Murakami H, Ikeda Y, Yamanishi H, Abe M, Matsuura B and Onji M.
Am J Clin Nutr, Vol.96(1), p90-101, Jul 2012.
# Exenatide, a glucagon-like peptide-1 receptor agonist, acutely inhibits intestinal lipoprotein production in healthy humans
Xiao C, Bandsma RH, Dash S, Szeto L, Lewis GF.
Arterioscler Thromb Vasc Biol. Vol.32(6), p1513-9, Jun 2012.
# Lowering of postprandial lipids in individuals with type 2 diabetes treated with alogliptin and/or pioglitazone: a randomised double-blind placebo-controlled study
Eliasson B, Moller-Goede D, Eeg-Olofsson K, Wilson C, Cederholm J, Fleck P, Diamant M, Taskinen MR, Smith U.
Diabetologia. Vol.55(4), p915-25, Apr 2012.
# Unacylated Ghrelin is associated with the isolated low HDL-cholesterol obese phenotypeindependently of insulin resistance and CRP level
Nogueira JP, Maraninchi M, Beliard S, Lorec AM, Berthet B, Begu-Le Corroller A, Dubois N, Grangeot R, Mattei C, Gaudart J, Nicolay A, Portugal H, Vialettes B,Valero R.
Nutr Metab (Lond).Vol.13;9(1):17. Mar 2012.
# Effect of short-term low- and high-fat diets on low-density lipoprotein particle size in normolipidemic subjects.
Guay V, Lamarche B, Charest A, Tremblay AJ, Couture P
Metabolism. Vol.61(1), p76-83, Jan 2012.
# The characteristics of remnantlipoproteins in the fasting andpostprandialplasma the fasting andpostprandialplasma
Nakajima K, Nakano T, Tokita Y, Nagamine T, Yatsuzuka S, Shimomura Y, Tanaka A, Sumino H, Nara M, Machida T, Murakami M.
Clinica Chimica Acta, Vol.413(13-14), p1077-86, Jul 2012.
# Exploring the value of apoB48 as a marker for atherosclerosis in clinical practice
Arash Alipour, Pedro Valdivielso, Jan Willem F. Elte, HansW. Janssen, Jose Rioja, Noe lle van der Meulen, Rob van Mechelen, Tjin L. Njo, Pedro Gonza´ lez-Santos, Arie P. Rietveld, Manuel Castro Cabezas
Eur J Clin Invest. Vol.42(7), p702-708, Jul 2012.
# Fasting APO B48 levels are associated with microalbuminuria in patients with type 2 diabetes
E. Lapice, P. Cipriano, L. Patti, G. Romano, O. Vaccaro and A. A. Rivellese
ACTA DIABETOLOGICA, Vol.49(5), p409-412, Oct 2012.
# Regulation of lipid metabolism-related gene expression in whole blood cells of normo- and dyslipidemic men after fish oil supplementation
S. Schmidt, J. Willers, F. Stahl, K-O. Mutz, T. Scheper, A. Hahn and J.P. Schuchardt.
Lipids in Health and Disease, 11:172, Dec 2012.
# Consumption of low doses of fat prevents the postprandial rise in chylomicron particle concentration and remnant accumulation in healthy normolipidaemic males
Anthony P. James and John C. Mamo
Journal of Nutritional Science, Vol.2012, e4 (8 pages)
# Exchanging Saturated Fatty Acids for (n-6) Polyunsaturated Fatty Acids in a Mixed Meal May Decrease Postprandial Lipemia and Markers of Inflammation and Endothelial Activity in Overweight Men
Christiaan J. Masson and Ronald P. Mensink
J. Nutr. Vol.141(5), p816-821, May 2011.
# Palmitic acid in the sn-2 position of triacylglycerols acutely influences postprandial lipid metabolism
Thomas AB Sanders, Androulla Filippou, Sarah E Berry, Sabine Baumgartner, and Ronald P Mensink
Am J Clin Nutr. Vol.94(6), p1433-1441, Dec 2011.
# Effect of Omega-3 Fatty Acids on Low Density Lipoprotein Subfraction, Adiponectin and Apolipoprotein B in Type 2 Diabetic Patients
Jun H, Ko J, Jung H, Yoon C, Kim T, Kwon M, Lee S, Suk J, Kim M, Kim D, Park JH.
Endocrinol Metab. Vol.26(3), p218-224, Sep 2011.
# Diet-induced dyslipidemia impairs reverse cholesterol transport in hamsters
Treguier M, Briand F, Boubacar A, Andre A, Magot T, Nguyen P, Krempf M, Sulpice T, Ouguerram K.
Eur J Clin Invest. Vol.41(9), p921-8, Sep 2011.
# Ezetimibe beneficially influences fasting and postprandial triglyceride-rich lipoproteins in type 2 diabetes
Bozzetto L, Annuzzi G, Corte GD, Patti L, Cipriano P, Mangione A, Riccardi G, Rivellese AA.
Atherosclerosis. Vol.217(1), p142-8, Jul 2011.
# Postprandial lipoprotein metabolism: VLDL vs chylomicrons
Nakajima K, Nakano T, Tokita Y, Nagamine T, Inazu A, Kobayashi J, Mabuchi H, Stanhope KL, Havel PJ, Okazaki M, Ai M, Tanaka A.
Clin Chim Acta. Vol.412(15-16), p1306-18, Jul 2011.
# Protocol for the measurement of fatty acid and glycerol turnover in vivo in baboons
Raul A. Bastarrachea, Sonya M. Veron, Vidya Vaidyanathan, Maggie Garcia-Forey, V. Saroja Voruganti, Paul B. Higgins, Elizabeth J. Parks
J Lipid Res. Vol.52(6), p1272-80, Jun 2011.
# Effects of acute hyperglucagonemia on hepatic and intestinal Lipoprotein production and clearancein healthy humans
Xiao C, Pavlic M, Szeto L, Patterson BW, Lewis GF.
Diabetes. Vol.60(2), p383-90, Feb 2011.
# Exploring the value of apoB48 as a marker for atherosclerosis in clinical practice
A. Alipour., P. Valdivielso., J. W. F. Elte., H.W. Janssen., J. Rioja., N. Meulen., R. Mechelen., T. L. Njo., P. G. Santos., A.P. Rietveld., and M. C. Cabezas.
Eur J Clin Invest, Vol.42(7), p702-8, Jul 2012.
# Atorvastatin increases intestinal expression of NPC1L1 in hyperlipidemic men
Tremblay, A.J, Lamarche, B., Lemelin, V., Hoos, L., Benjannet, S., Seidah, N.G., Davis Jr., H.R., and Couture, P.
The Journal of Lipid Research, Vol.52(3), p558-868, Mar 2011.
# Effect of Sitagliptin Therapy on Postprandial Lipoprotein Levels in Patients with Type 2 Diabetes
Tremblay, A.J., Lamarche, B., Deacon, C.F., Weisnagel, S.J. and Couture, P.
Diabetes, Obesity and Metabolism, Vol.13(4), p366-373, Apr 2011.
# Particle Size of ApoB-48 Carrying Lipoproteins in Remnant Lipoproteins Isolated from Postprandial Plasma
Nakano, T., Tanaka, A., Okazaki, M., Tokita, Y., Nagamine, T. and Nakajima, K.
Ann Clin Biochem, Vol.48, p57-64, Jan 2011.
# Resistance exercise but not aerobic exercise lowers remnant-like lipoprotein particle cholesterol in type 2 diabetes: a randomized controlled trial.
Gavin C, Sigal RJ, Cousins M, Menard ML, Atkinson M, Khandwala F, Kenny GP, Proctor S, Ooi TC; Diabetes Aerobic and Resistance Exercise (DARE) trial investigators.
Atherosclerosis. Vol.213(2), p552-7, Dec 2010.
# Jejunal Wall Triglyceride Concentration of Morbidly Obese Persons Is Lower in Those with Type 2 Diabetes Mellitus
Soriguer, F., Garcia-Serrano, S., Garrido-Sanchez, L., Gutirrez-Repiso, C., Rojo-Martinez, G., Garcia-Escobar, E., Garcis-Arnes, J., Gallego-Perales, JL., Delgano, V. and Garcia-Fuentes, E.
J Lipid Res. Vol.51(12), p3516-23, Dec 2010.
# Postprandial lipid and apolipoprotein responses following three consecutive meals associate with liver fat content in type 2 diabetes and the metabolic syndrome
Tushuizen ME, Pouwels PJ, Bontemps S, Rustemeijer C, Matikainen N, Heine RJ, Taskinen MR, Diamant M.
Atherosclerosis. Vol.211(1), p308-14, Jul 2010.
# Chylomicronemia with low postheparin lipoprotein lipase levels in the setting of GPIHBP1 defects
Franssen R, Young SG, Peelman F, Hertecant J, Sierts JA, Schimmel AW, Bensadoun A, Kastelein JJ, Fong LG, Dallinga-Thie GM, Beigneux AP
Circ Cardiovasc Genet. Vol.3(2), p169-78, Apr 2010.
# Effect of Low Concentration of Diacylglycerol on Mildly Postprandial Hypertriglyceridemia
Saito, S., Yamaguchi, T., Shoji, K., Hibi, M., Sugita, T. and Takase, H.
Atherosclerosis, Vol.213(2), p 539-544, Dec 2010.
# Insulin Acutely Inhibits Intestinal Lipoprotein Secretion in Human in Part by Suppressing Plasma Free Fatty Acids
Pavlic, M., Xiao, C., Szeto, L., Patterson, B.W. and Lewis, G.F.
Diabetes, Vol.59(3), p580-287, 2010.
# Increased Serum Apolipoprotein B48 Concentration in Patients with Metabolic Syndrome
Kinoshita,M.,Ohnishi,H.,Maeda,T.,Yoshimura,N.,Takeoka,Y.,Yasuda,D.,Kusano,J.,Mashimo,Y., Saito,S.,Shimamoto,K.and Teramoto,T.
J Atheroscler Thromb, Vol.16(4), p517-522, Aug 2009.
# Familial Combined Hyperlipidemia Is Associated With Alterations in the Cholesterol Synthesis Pathway
Himbergen, T. M., Otokozawa, S., Matthan, N. R., Schaefer, E. J., Buchsbaum, A., Ai, M., Tits, L. J. H., Graaf, J., Stalenhoef, A. F. H.
Arterioscler Thromb Vasc Biol, Vol.30(1), p113-120, Jan 2010.
# Postprandial apolipoprotein B48 is associated with asymptomatic peripheral arterial disease: A study in patients with type 2 diabetes and controls
Valdivielso, P., Puerta, S., Rioja, J., Alonso, I., Ariza, M. J., Sanchez-Chaparro, M. A., Palacios, R., Gonzalez-Santos, P.
Clinica Chimica Acta, Vol.411(5-6), p433-437, Mar 2010.
# Chylomicronemia With a Mutant GPIHBP1 (Q115P) That Cannot Bind Lipoprotein Lipase
Beigneux, A. P., Franssen, R., Bensadoun, A., Gin, P., Melford. K., Peter, J., Walzem, R. L., Weinstein, M. M., Davies, B. S. J., Kuivenhoven, J. A., Kastelein, J. J. P., Fong, L. G., Dallinga-Thie, G. M., Young, A. G.
Arterioscler Thromb Vasc Biol, Vol.29, p956-962, Jun 2009.
# Omega 3 fatty acids induce a markerd reduction of apolipoprotein B48 when added to fluvastatin in patients with type 2 diabetes and mixed hyperlipidemia
Valdivielso,P.,Rioja,J.,Garcia-Arias,C.,Sanchez-Chaparro,MA.,Gonzalez-Santos,P.
Cardiovasc Diabetol, 8;8:1, Jan 2009.
# Effects of intensive atorvastatin and rosuvastatin treatment on apolipoprotein B-48 and remnant lipoprotein cholesterol levels
Seiko Otokozawa,Masumi Ai,Thomas Van Himbergen,Bela F.Asztalos,Akira Tanaka, Evan A.Stein,Peter H.Jones and Ernst J.Schaefer
Atheroscleroisis, Vol.205(1), p197-201, Jul 2009.
# Fasting and postprandial apolipoprotein B-48 levels in healthy,obese,and hyperlipidemic subjects
Otokozawa,S.,Ai,M., Diffenderfer,MR., Asztalos,BF.,Tanaka,A., Lamon-Fava,S., Schaefer,EJ.
Metabolism Clinical and Experimental, Vol.58(11), p1536-1542, Nov 2009.
# Detection of apolipoprotein B-48 and B-100 carrying particles in lipoprotein fractions extracted from human aortic atherosclerotic plaques in sudden cardiac death cases.
Nakano, T., Nakajima, K., Niimi, M., Fujita, M.Q., Nakajima, Y., Takeichi, S, Kinoshita, M., Matsushima, T., Teramoto, T., and Tanaka, A.
Clinica Chimica Acta, Vol.390(1-2), p38-43, Apr 2008.
# Plasma fasting and postprandial apolipoprotein B48 are increased only in type2 diabetes with atherosclerosclerosis
P.Valdivielso,J.Rioja,S.Puerta,M.J.Ariza-Corbo,M.A.Sanchez-Chaparro, I.Alonso and P.Gonzalez-Santos
Atherosclerosis Supplements, Vol.9(2), p87-88, Sep 2008.
# Postprandial Hyperlipidemia and Atherosclerosis
Teramoto, T.
Atherosclerosis Supplements, Vol.9, p83-102, 2008.
# Decreased lipoprotein lipase activity and increased postprandial concentrations of triglyceride-rich lipoproteins in offspring of elderly survivors of myocardial infarction.
Lakhal, S., Borvik, T., Nordoy, A., and Hansen, J.B.
Nutrition, Metabolism and Cardiovascular Diseases, Vol.18,(10), p700-706, Dec 2008.
Lamon-Fava S,Diffenderfer MR,Barrett PH,Buchsbaum A,Nyaku M,Horvath KV,Asztalos BF, Otokozawa S,Ai M,Matthan NR,Lichtenstein AH,Dolnikowski GG,Schaefer EJ.
Arterioscler Thromb Vasc Biol. Vol.28(9), p1672-8, Sep 2008.
# ApoB-100 carrying lipoprotein, but not apoB-48, is the major subset of proatherogenic remnant-like lipoprotein particles detected in plasma of sudden cardiac death cases.
Nakajima, K., Nakajima, Y., Takeichi, S., and Fijita, M.Q.
Atherosclerosis, Vol.194(2), p473-482, Oct 2007.
# Involvement of intestinal alkaline phosphatase in serum apolipoprotein B-48 level and its association with ABO and secretor blood group types
Nakano, T., Shimanuki, T., Matsushita, M., Koyama, I., Inoue, I., Katayama, S., Alpers, D. H., Komoda, T.
Biochemical and Biophysical Research Communications, Vol.341, p33-38, 2006.
# Determination of apolipoprotein B-48 in serum by a sandwich ELISA
Kinoshita, M., Kojima, M., Matsushima, T., and Teramoto, T.
Clinica Chimaca Acta, Vol.351(1-2), p115-120, Jan 2005.
Presentations at scientific meetings
# Fasting and Postprandial Apo-B48 are Increased in Patients with Type 2 diabetes with Atherosclerosis
Valdivielso, P., Puerta, S., Rioja, J., Ariza, M., Hornos, A., Garcia-Arias, C., Sanchez-Chaparro, M., Gonzalez-Santos, P.(Univ. of Malaga)
77th Congress of the European Atherosclerosis Society, April 26-29, 2008, Istanbul, Turkey, Poster sessions, PO20-228
# Reduced Postprandial Concentration of Apolipoprotein B-48 with Camelina Oil
Vaananen, M., Ahotupa, M., Vasankari, T. M., Vasankari, T. J.(University of Turku)
76th Congress of the European Atherosclerosis Society, June 10-13, 2007, Helsinki, Finland, Poster sessions, PO20-619
# Apolipoprotein B-48 in Lipoprotein Fraction Extracted from Human Aortic Plaque and Plasma from Sudden Cardiac Death Cases
Nakano, T., Niimi, M., Nakajima, K., Fujita, M., Nakajima, Y., Takeichi, S., Tanaka, A., Matsushima, T., Kinoshita, M,. Teramoto, T.
(Jimro Co., Ltd., Keio Univ., Tokai Univ., Kagawa Nutrition Univ., Tsukuba Memorial Hospital., Teikyo Univ.)
76th Congress of the European Atherosclerosis Society, June 10-13, 2007, Helsinki, Finland, Poster sessions, PO3-63
# Concentration of Apolipoprotein B48 in Fasting Serum is an Important Marker of Postrandial Hyperlipidemia
Takenaka, H., Kinoshita, H., Maeda, T., Taki, M., Takao, K., Kusano, J., Yoshimura, N., Fujita, M., Teramoto, T.(Teikyo Univ. Sch. Of Med.)
XIV International Symposium on Atherosclerosis, Rome, Italy, June 18-22, 2006 Poster Session, Th-P15:76
# Concentration of apolipoprotein B48 in fasting serum is an important marker of postprandial hyperlipidemia.
Hirota, D., Kinosita, M., Maeda, T., suda, T., Taki, M., Kusano, J., Takenaka, H., Yoshimura, N., and Teramoto, T.(Teikyo Univ. Sch. of Med. Int. Med.)
The 37th Japan Atherosclerosis Society Annual Meeting, 2005, English session ES-J8,Proceeding p.185
# 内臓脂肪量が食後血清脂質に与える影響と脂質レス食品の有用性
田中 明，坂本朱子，梶本修身，梶本佳孝，中島克行，中野隆光，藍 真澄，石崎太一，藤塚真紀，谷本浩之
(関東学院大学，株式会社総合医科学研究所，大阪外国語大学健康管理センター，株式会社日本抗体研究所，東京医科歯科大学，味の素株式会社食品研究所）
第37回 日本動脈硬化学会総会，プログラム・抄録集 演題番号193
# 食後高脂血症の指標としての空腹時アポ蛋白B48濃度の意義
廣田大輔，木下 誠，前田朝美，須田隆興，瀧 雅成，草野 淳，高尾康介，竹中英樹，吉村中行，寺本民生（帝京大学医学部内科）
第37回 日本動脈硬化学会総会，プログラム・抄録集 演題番号194
# 冠動脈疾患患者におけるアポ蛋白B48の食事による変動の検討
須田隆興，前田朝美，廣田大輔，瀧 雅成，高尾康介，竹中英樹，草野 淳，藤田美峰子，木下 誠，寺本民生（帝京大学医学部内科）